RS5985 F13A1

Health Risk Chr 6:6318561 snv missense variant

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What This Variant Does

"Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII gen...

Associated Conditions

Myocardial infarction

protection against

Venous thrombosis

Factor XIII

A subunit

deficiency of

Myocardial infarction

protection against

Venous thrombosis

Factor XIII

A subunit

deficiency of

GWAS Studies (5)

Trait	Risk Allele	OR / Beta	P-value	Study
End-stage coagulation	C	OR: 1.08	3E-186	PubMed
ERI1 protein levels	A	β: 0.071	4E-24	PubMed
Serum levels of protein SERPINF2	A	OR: 0.15	5E-17	PubMed
Serum levels of protein FRS2	A	OR: 0.16	4E-15	PubMed
Serum levels of protein FN1	A	OR: 0.15	7E-13	PubMed

Population Frequencies

gnomAD ALL

23.5%

1kG AFR

16.4%

1kG ALL

85.2%

1kG AMR

26.9%

1kG EAS

0.2%

1kG EUR

24.2%

1kG SAS

90.7%

Other Variants in F13A1