RS582757 Unknown gene

Other Chr 6:137876687
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What This Variant Does
"rs582757 variant is located within an intron of TNFAIP3 gene that encodes for tumor necrosis factor ..."
GWAS Studies (8)
Trait Risk Allele OR / Beta P-value Study
Psoriasis C OR: 1.23 2E-25 PubMed
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) 1E-16 PubMed
Psoriasis (PheCode 696.4) C β: 0.097 1E-16 PubMed
Psoriasis T OR: 0.12 3E-16 PubMed
Psoriasis vulgaris (PheCode 696.41) C β: 0.093 1E-14 PubMed
neutrophil (absolute count, mean, inv-norm transformed) C β: 0.025 9E-14 PubMed
Psoriasis or type 2 diabetes (trans-disease meta-analysis) C OR: 1.08 3E-13 PubMed
Psoriasis T OR: 1.25 6E-12 PubMed
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