RS5174 LRP8
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What This Variant Does
"rs5174 encodes a variant of the LRP8 gene, encoding the low density lipoprotein receptor-related 8 p...
Associated Conditions
Myocardial infarction
susceptibility to
1
Myocardial infarction
susceptibility to
1
GWAS Studies (12)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Low-density lipoprotein receptor-related protein 8 levels | T | OR: 0.35 | 6E-47 | PubMed |
| Vertex-wise cortical thickness | T | OR: 11.11 | 1E-28 | PubMed |
| Whole brain restricted directional diffusion (multivariate analysis) | — | — | 1E-26 | PubMed |
| Vertex-wise sulcal depth | T | OR: 10.6 | 3E-26 | PubMed |
| Cortical thickness | T | — | 1E-17 | PubMed |
| Brain morphology (MOSTest) | — | — | 9E-15 | PubMed |
| Personality traits or cognitive traits (multivariate analysis) | — | — | 1E-13 | PubMed |
| Cortical surface area | T | — | 2E-12 | PubMed |
| Vertex-wise cortical surface area | T | OR: 6.95 | 4E-12 | PubMed |
| Number of sexual partners in opposite-sex sexual behavior | C | OR: 0.13 | 2E-11 | PubMed |
| Brain shape (segment 15) | — | — | 6E-10 | PubMed |
| General risk tolerance (MTAG) | T | β: 0.007 | 1E-8 | PubMed |
Other Variants in LRP8