RS495828 Unknown gene
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What This Variant Does
"A common variant of the ABO gene protects against hypertension in a Spanish population. Pharmacogene..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Hemoglobin levels | T | β: 0.065 | 1E-124 | PubMed |
| LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) | T | — | 4E-103 | PubMed |
| LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) | T | — | 5E-69 | PubMed |
| Hematological and biochemical traits | T | OR: 0.31 | 4E-59 | PubMed |
| Height | T | β: 0.011 | 3E-46 | PubMed |
| Protein levels in obesity | — | OR: 0.5 | 9E-40 | PubMed |
| DSGEGDFXAEGGGVR-to-ADpSGEGDFXAEGGGVR ratio | T | β: 0.088 | 6E-34 | PubMed |
| Cadherin-5 levels | — | OR: 0.33 | 4E-29 | PubMed |
| Hemoglobin A1c levels | T | β: 0.053 | 2E-24 | PubMed |
| Hemoglobin levels | T | OR: 0.1 | 1E-19 | PubMed |
| SCARF1 protein levels | T | β: 0.057 | 5E-17 | PubMed |
| Venous thromboembolism | T | OR: 1.65 | 3E-16 | PubMed |
| Blood protein levels in cardiovascular risk | T | OR: 0.17 | 6E-13 | PubMed |
| Apolipoprotein B to apolipoprotein A1 ratio (UKB data field 23441) | T | β: 0.041 | 7E-13 | PubMed |
| F2R protein levels | T | β: 0.05 | 9E-13 | PubMed |
| COVID-19 or coronary artery disease (pleiotropy) | T | OR: 0.93 | 1E-12 | PubMed |
| COVID-19 or hypertension (pleiotropy) | T | OR: 0.95 | 2E-12 | PubMed |
| Red blood cell count | T | β: 0.091 | 3E-12 | PubMed |
| Coronary artery disease | T | β: 0.06 | 9E-12 | PubMed |
| Breast cancer or ovarian cancer (pleiotropy) | G | — | 7E-11 | PubMed |