RS459552 APC

Health Risk Chr 5:112841058 snv missense variant

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What This Variant Does

"[OMIM:?]

Associated Conditions

Hereditary cancer-predisposing syndrome

Familial adenomatous polyposis 1

Hereditary cancer-predisposing syndrome

Familial adenomatous polyposis 1

GWAS Studies (6)

Trait	Risk Allele	OR / Beta	P-value	Study
Height	T	β: 0.017	5E-104	PubMed
Body mass index	T	β: 0.011	7E-12	PubMed
Body mass index	A	β: 0.013	8E-12	PubMed
Body mass index	A	β: 0.013	8E-12	PubMed
Body mass index	T	β: 0.013	1E-9	PubMed
Body mass index	T	β: 0.012	5E-9	PubMed

Population Frequencies

gnomAD ALL

22.4%

1kG AFR

0.9%

1kG ALL

86.5%

1kG AMR

81.8%

1kG EAS

9.9%

1kG EUR

76.5%

1kG SAS

79.6%

Other Variants in APC