RS4430796 Unknown gene
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What This Variant Does
"rs4430796 is a SNP in the TCF2 gene on chromosome 17q12, associated with increased risk for prostate..."
GWAS Studies (17)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Prostate cancer | A | OR: 1.22 | 1E-132 | PubMed |
| Prostate cancer | A | OR: 1.37 | 5E-27 | PubMed |
| Prostate cancer | — | OR: 0.83 | 8E-26 | PubMed |
| Type 2 diabetes | A | β: 0.083 | 3E-15 | PubMed |
| Prostate cancer | A | OR: 1.22 | 1E-11 | PubMed |
| Type 2 diabetes | G | OR: 1.19 | 2E-11 | PubMed |
| Serum prostate-specific antigen levels | A | OR: 9.4 | 6E-11 | PubMed |
| Endometrial cancer | A | OR: 1.19 | 7E-10 | PubMed |
| Type 2 diabetes | G | OR: 1.13 | 9E-10 | PubMed |
| Prostate cancer | A | OR: 1.18 | 1E-9 | PubMed |
| Incident hormone-sensitive cancer | G | β: 0.003 | 3E-9 | PubMed |
| Hormone-sensitive cancer | G | β: 0.004 | 2E-8 | PubMed |
| Prostate cancer | A | OR: 1.23 | 6E-8 | PubMed |
| Type 2 diabetes | G | OR: 1.14 | 2E-6 | PubMed |
| Type 2 diabetes | G | OR: 1.11 | 4E-6 | PubMed |
| Prostate cancer (SNP x SNP interaction) | — | OR: 1.27 | 5E-6 | PubMed |
| Prostate cancer | A | OR: 1.19 | 8E-6 | PubMed |