RS4420638 Unknown gene
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What This Variant Does
"Apolipoprotein E ApoE status is technically defined by two different SNPs, rs429358 and rs7412. This...
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Apolipoprotein B levels | G | OR: 0.27 | 1E-1788 | PubMed |
| Low density lipoprotein cholesterol levels | G | OR: 0.22 | 1E-1192 | PubMed |
| C-reactive protein levels | G | OR: 0.22 | 3E-1177 | PubMed |
| Total cholesterol levels | G | OR: 0.19 | 2E-905 | PubMed |
| C-reactive protein levels | A | OR: 0.23 | 1E-305 | PubMed |
| Alzheimer's disease or family history of Alzheimer's disease | G | — | 4E-288 | PubMed |
| C-reactive protein levels or LDL-cholesterol levels (pleiotropy) | A | — | 1E-283 | PubMed |
| C-reactive protein levels or total cholesterol levels (pleiotropy) | A | — | 4E-249 | PubMed |
| Alzheimer's disease | G | — | 2E-202 | PubMed |
| Apolipoprotein A1 levels | G | β: 0.095 | 2E-194 | PubMed |
| LDL cholesterol | G | OR: 0.23 | 2E-178 | PubMed |
| C-reactive protein levels or triglyceride levels (pleiotropy) | A | — | 2E-171 | PubMed |
| C-reactive protein levels or HDL-cholesterol levels (pleiotropy) | A | — | 2E-164 | PubMed |
| Low density lipoprotein cholesterol levels | A | OR: 0.16 | 3E-162 | PubMed |
| Cholesterol, total | G | OR: 0.2 | 1E-149 | PubMed |
| Alzheimer's disease | — | OR: 3.45 | 8E-149 | PubMed |
| LDL cholesterol | G | OR: 7.14 | 9E-147 | PubMed |
| C-reactive protein levels | A | OR: 0.24 | 9E-139 | PubMed |
| Total cholesterol levels | A | OR: 0.14 | 3E-120 | PubMed |
| Cholesterol, total | G | OR: 6.83 | 5E-111 | PubMed |