RS4272 Unknown gene
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What This Variant Does
"One of 42 more SNPs associated with rheumatoid arthritis based on a meta-analysis of 30,000 patients..."
GWAS Studies (19)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Monocyte side scatter | G | β: 0.097 | 3E-30 | PubMed |
| Pulse pressure | G | OR: 11.14 | 8E-29 | PubMed |
| Granulocyte percentage of myeloid white cells | G | β: 0.049 | 2E-28 | PubMed |
| systolic blood pressure (SBP, maximum, inv-normal transformed) | A | β: 0.03 | 2E-24 | PubMed |
| Multi-trait sex score | — | — | 5E-21 | PubMed |
| Eosinophill count (UKB data field 30150) | G | β: 0.022 | 2E-19 | PubMed |
| Multi-trait sex score | — | — | 4E-18 | PubMed |
| Pulse pressure | G | OR: 8.36 | 6E-17 | PubMed |
| Basophil percentage of white cells variance | G | β: 0.024 | 3E-16 | PubMed |
| Waist circumference adjusted for body mass index | G | β: 0.031 | 4E-16 | PubMed |
| Mitochondrial DNA copy number (raw) | A | β: 0.035 | 1E-15 | PubMed |
| Cerebrovascular disease (PheCode 433) | A | β: 0.054 | 2E-14 | PubMed |
| Pulse pressure | G | OR: 7.31 | 3E-13 | PubMed |
| Systolic blood pressure | G | OR: 6.76 | 1E-11 | PubMed |
| Basophil count variance | G | β: 0.019 | 3E-11 | PubMed |
| Eosinophil count | G | β: 0.026 | 4E-9 | PubMed |
| Rheumatoid arthritis | G | OR: 1.1 | 1E-8 | PubMed |
| Rheumatoid arthritis | A | β: 0.097 | 3E-7 | PubMed |
| Systolic blood pressure | G | OR: 5.07 | 4E-7 | PubMed |