RS4246215 Unknown gene
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What This Variant Does
"Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk. [GWAS:Non..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Lysophosphatidylethanolamine_22:4_[M-H]1- levels | T | OR: 0.33 | 3E-256 | PubMed |
| Lysophosphatidylcholine_20:4_[M+H]1+ levels | T | OR: 0.39 | 5E-236 | PubMed |
| Cholesterol to Total Lipids in Medium LDL percentage | T | β: 0.089 | 7E-194 | PubMed |
| Phosphatidylethanolamine_38:4_[M-H]1- levels | T | OR: 0.22 | 7E-142 | PubMed |
| Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid) | T | β: 0.07 | 1E-139 | PubMed |
| Cholesteryl ester_20:5_[M+NH4]1+ levels | T | OR: 0.29 | 3E-138 | PubMed |
| Phosphatidylcholine_37:4_[M+H]1+/Phosphatidylethanolamine_40:4_[M+H]1+/Phosphatidate_42:5_[M+NH4]1+ levels | T | OR: 0.36 | 1E-119 | PubMed |
| Phosphatidylcholine_38:5_[M+H]1+/Phosphatidylethanolamine_41:5_[M+H]1+/Phosphatidate_43:6_[M+NH4]1+ levels | T | OR: 0.34 | 4E-111 | PubMed |
| Fatty acid(20:4)_[M-H]1- levels | T | OR: 0.18 | 4E-109 | PubMed |
| Phosphatidylcholine_36:3_[M+H]1+/Phosphatidylethanolamine_39:3_[M+H]1+/Phosphatidate_41:4_[M+NH4]1+ levels | T | OR: 0.32 | 1E-104 | PubMed |
| Phosphatidylinositol_36:3_[M-H]1- levels | T | OR: 0.21 | 8E-88 | PubMed |
| Phosphatidylcholine_35:3_[M+H]1+/Phosphatidylethanolamine_38:3_[M+H]1+/Phosphatidate_40:4_[M+NH4]1+ levels | T | OR: 0.21 | 8E-88 | PubMed |
| Diacylglycerol_38:3_[M+H-H2O]1+ levels | T | OR: 0.16 | 4E-87 | PubMed |
| Cholesterol to Total Lipids in Medium LDL percentage | T | β: 0.062 | 4E-84 | PubMed |
| Phosphatidylethanolamine_39:4_[M-H]1- levels | T | OR: 0.18 | 2E-77 | PubMed |
| Phosphatidylcholine_35:4_[M+H]1+/Phosphatidylethanolamine_38:4_[M+H]1+/Phosphatidate_40:5_[M+NH4]1+ levels | T | OR: 0.22 | 3E-77 | PubMed |
| Phosphatidylcholine_34:2_[M+H]1+/Phosphatidylethanolamine_37:2_[M+H]1+/Phosphatidate_39:3_[M+NH4]1+ levels | T | OR: 0.22 | 1E-76 | PubMed |
| Phosphatidylethanolamine_38:3_[M-H]1- levels | T | OR: 0.14 | 3E-74 | PubMed |
| Diacylglycerol_38:5_[M+H-H2O]1+ levels | T | OR: 0.16 | 9E-74 | PubMed |
| Phosphatidylcholine_31:2_[M+H]1+/Phosphatidylethanolamine_34:2_[M+H]1+/Phosphatidate_36:3_[M+NH4]1+ levels | T | OR: 0.22 | 3E-69 | PubMed |