Genetic variant

rs3820897

rs3820897 is a single-letter difference in human DNA, on chromosome 2. Carrying it does not, on its own, mean you have or will develop any condition.

Register free Do I have this variant?

What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs3820897 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

Genetic Variation of COLEC10 and COLEC11 and Association with Serum Levels of Collectin Liver 1 (CL-L1) and Collectin Kidney 1 (CL-K1)

From SNPedia

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs3820897, if your test read this position.

Register free Upload DNA Log in

Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

Upload blood results

What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
Register free Upload DNA Upload blood results Ask Dr. Hemsworth

This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs3820897
Position
chr2:3594771

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
Interleukin-19 levels (IL19.3035.80.2) C OR 0.81 3E-158 PubMed
Serum levels of protein IL19 T OR 0.58 4E-146 PubMed
MASP1 protein levels C OR 0.16 3E-122 PubMed
Peptidyl-prolyl cis-trans isomerase B levels T OR 0.38 6E-105 PubMed
High affinity nerve growth factor receptor levels T OR 0.34 2E-86 PubMed
FCN1 protein levels C OR 0.13 5E-80 PubMed
Blood protein levels C OR 0.58 7E-79 PubMed
PLXDC2 protein levels C OR 0.14 4E-74 PubMed
high density lipoprotein cholesterol (HDLC, mean, inv-norm transformed) T β 0.062 4E-57 PubMed
Gamma glutamyl transferase levels T β 0.026 2E-52 PubMed
Sialic acid-binding Ig-like lectin 14 levels (SIGLEC14.8248.222.3) C OR 0.48 3E-49 PubMed
high density lipoprotein cholesterol (HDLC, minimm, inv-norm transformed) T β 0.054 9E-45 PubMed
Collectin-10 levels (COLEC10.6558.5.3) C OR 0.42 2E-38 PubMed
Acid sphingomyelinase-like phosphodiesterase 3a levels T OR 0.22 2E-38 PubMed
High density lipoprotein cholesterol levels — — 8E-37 PubMed
Granulocyte colony-stimulating factor receptor levels T OR 0.2 1E-30 PubMed
Regulator of G-protein signaling 1 levels T OR 0.18 3E-26 PubMed
Interleukin-22 receptor subunit alpha-1 levels T OR 0.17 1E-24 PubMed
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 levels T OR 0.18 2E-24 PubMed
Phospholipids to Total Lipids in Medium HDL percentage C β 0.03 4E-24 PubMed

Sources