RS2571445 Unknown gene
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What This Variant Does
"[GWAS:Lung function]"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Immature fraction of reticulocytes | G | β: 0.04 | 4E-67 | PubMed |
| Immature reticulocyte fraction (UKB data field 30280) | G | β: 0.033 | 1E-60 | PubMed |
| Lung function (FEV1) | A | OR: 14.72 | 5E-49 | PubMed |
| High light scatter reticulocyte count | G | β: 0.032 | 7E-45 | PubMed |
| High light scatter reticulocyte percentage of red cells | G | β: 0.032 | 1E-44 | PubMed |
| Forced expiratory volume in 1 second (FEV1) | — | — | 1E-43 | PubMed |
| High light scatter reticulocyte percentage (UKB data field 30290) | G | β: 0.027 | 5E-42 | PubMed |
| FEV1 | A | β: 0.029 | 7E-33 | PubMed |
| Lung function (FEV1/FVC) | — | — | 6E-31 | PubMed |
| Forced expiratory volume in 1 second FEV1 Z score (UKB data field 20256) | G | β: 0.023 | 5E-30 | PubMed |
| Immature fraction of reticulocytes | G | β: 0.041 | 5E-30 | PubMed |
| Chronic obstructive pulmonary disease liability (machine learning-based score) | A | β: 0.024 | 8E-30 | PubMed |
| Forced vital capacity (FVC) | — | — | 1E-27 | PubMed |
| FEV1 FVC ratio Z score (UKB data field 20258) | G | β: 0.018 | 7E-21 | PubMed |
| Forced expiratory volume (baseline) | A | β: 0.016 | 1E-20 | PubMed |
| Lung function (FVC) | A | β: 0.022 | 5E-20 | PubMed |
| Bicarbonate (maximum, inv-norm transformed) | A | β: 0.024 | 2E-19 | PubMed |
| Reticulocyte count (UKB data field 30250) | G | β: 0.018 | 3E-19 | PubMed |
| Reticulocyte percentage (UKB data field 30240) | G | β: 0.018 | 9E-19 | PubMed |
| High light scatter reticulocyte count | G | β: 0.032 | 2E-18 | PubMed |