RS2186369 Unknown gene
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What This Variant Does
"[GWAS:IgG glycosylation]"
GWAS Studies (14)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Percentage of FA2BG1 in total neutral plasma glycans (GPn) (GP63) | G | OR: 0.3 | 4E-37 | PubMed |
| Neutral glycans = absence of N-acetylneuraminic acid (multivariate analysis) | G | β: 0.03 | 2E-34 | PubMed |
| IgG glycosylation patterns | G | OR: 0.37 | 6E-13 | PubMed |
| IgG glycosylation | G | OR: 0.29 | 1E-12 | PubMed |
| IgG monogalactosylation phenotypes (multivariate analysis) | G | — | 1E-12 | PubMed |
| IgG N-glycosylation phenotypes (multivariate analysis) | G | — | 3E-11 | PubMed |
| IgG fucosylation phenotypes (multivariate analysis) | G | — | 3E-11 | PubMed |
| IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) | G | — | 4E-11 | PubMed |
| Immunoglobulin N-glycan 11 levels | T | OR: 0.27 | 5E-11 | PubMed |
| IgG galactosylation phenotypes (multivariate analysis) | G | — | 3E-10 | PubMed |
| IgG digalactosylation phenotypes (multivariate analysis) | G | — | 4E-10 | PubMed |
| IgG disialylation phenotypes (multivariate analysis) | G | — | 1E-7 | PubMed |
| IgG glycosylation | T | β: 0.067 | 2E-7 | PubMed |
| IgG sialylation phenotypes (multivariate analysis) | G | — | 1E-6 | PubMed |