Genetic variant

rs2070895

rs2070895 is a single-letter difference in human DNA, on chromosome 15. Carrying it does not, on its own, mean you have or will develop any condition.

Register free Do I have this variant?

What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs2070895 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs2070895, if your test read this position.

Register free Upload DNA Log in

Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

Upload blood results

What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
Register free Upload DNA Upload blood results Ask Dr. Hemsworth

This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs2070895
Position
chr15:58431740

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
Triglycerides in very large HDL A OR 0.26 6E-2419 PubMed
Cholesteryl Esters to Total Lipids in Small HDL percentage A OR 0.25 2E-2314 PubMed
Free Cholesterol to Total Lipids in Small HDL percentage A OR 0.24 7E-2290 PubMed
Triglycerides in large LDL A OR 0.23 1E-1910 PubMed
Concentration of very large HDL particles A OR 0.19 4E-1684 PubMed
Triglycerides in very large HDL A OR 0.29 2E-1625 PubMed
Triglycerides to Total Lipids in Medium LDL percentage A OR 0.21 1E-1624 PubMed
Triglycerides in HDL A OR 0.2 8E-1580 PubMed
Cholesterol to Total Lipids in Very Large HDL percentage A OR 0.29 7E-1544 PubMed
Phospholipids to Total Lipids in Large LDL percentage A OR 0.2 3E-1482 PubMed
Triglycerides in LDL A OR 0.2 2E-1463 PubMed
Phosphatidylcholine levels A OR 0.17 2E-1221 PubMed
Free Cholesterol to Total Lipids in Medium HDL percentage A OR 0.15 3E-1152 PubMed
Cholesterol to Total Lipids in Small HDL percentage A OR 0.17 7E-1111 PubMed
Cholesterol esters in very large HDL A OR 0.15 1E-1107 PubMed
Cholesterol levels in very large HDL A OR 0.15 9E-1096 PubMed
Cholesterol to Total Lipids in IDL percentage A OR 0.16 1E-1044 PubMed
Triglycerides in medium LDL A OR 0.17 2E-1031 PubMed
Cholesterol to Total Lipids in Very Large HDL percentage A OR 0.25 1E-1007 PubMed
Free cholesterol in very large HDL A OR 0.15 2E-997 PubMed

Sources