RS2070600 Unknown gene
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What This Variant Does
"rs2070600 (Gly82Ser) is a non-synonymous snp located in exon 3 of AGER (Advanced Glycation End produ..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| FEV1 FVC ratio Z score (UKB data field 20258) | T | OR: 0.12 | 3E-239 | PubMed |
| Lung function (FEV1/FVC) | T | OR: 32.21 | 2E-227 | PubMed |
| Lung function (FEV1/FVC) | T | OR: 0.15 | 3E-189 | PubMed |
| SFTPD protein levels | T | OR: 0.21 | 3E-171 | PubMed |
| Advanced glycosylation end product-specific receptor, soluble levels | T | OR: 0.65 | 1E-113 | PubMed |
| Peak expiratory flow | T | β: 0.073 | 2E-45 | PubMed |
| Advanced glycosylation end product-specific receptor, soluble levels (AGER.4125.52.2) | T | OR: 0.57 | 4E-33 | PubMed |
| Serum levels of protein AGER | T | OR: 0.52 | 1E-31 | PubMed |
| Lung function (FEV1/FVC) | T | OR: 0.14 | 3E-25 | PubMed |
| Peak expiratory flow (UKB data field 3064) | T | β: 0.033 | 1E-22 | PubMed |
| Blood protein levels | — | OR: 0.71 | 3E-22 | PubMed |
| Pulmonary function (smoking interaction) | — | — | 1E-21 | PubMed |
| Chronic obstructive pulmonary disease | C | OR: 1.21 | 1E-17 | PubMed |
| Chronic obstructive pulmonary disease | C | OR: 1.19 | 1E-16 | PubMed |
| Soluble receptor for advanced glycation end-product levels | T | OR: 0.39 | 9E-16 | PubMed |
| Asthma | — | OR: 1.15 | 1E-15 | PubMed |
| Pulmonary function | T | β: 0.088 | 3E-15 | PubMed |
| Lung function (FVC) | T | β: 0.038 | 8E-15 | PubMed |
| Pulmonary function | T | OR: 1 | 3E-14 | PubMed |
| Blood protein levels in cardiovascular risk | T | OR: 0.37 | 5E-12 | PubMed |