Genetic variant
rs1906252
rs1906252 is a single-letter difference in human DNA, on chromosome 6. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs1906252 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
Location: chr6:98102413 - 98102413(1) Variant Alleles: C/A Ancestral Allele: C Minor Allele: A Minor...
From SNPedia
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs1906252, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs1906252
- Position
- chr6:98102413
Genome-wide association studies (17)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Attention deficit hyperactivity disorder or autism spectrum disorder or intelligence (pleiotropy) | — | — | 4E-42 | PubMed |
| Intelligence | A | OR 11.55 | 7E-31 | PubMed |
| Phospholipids to Total Lipids in Very Large HDL percentage | A | β 0.02 | 6E-28 | PubMed |
| Cognitive performance | A | β 0.031 | 4E-27 | PubMed |
| Cognitive aspects of educational attainment | C | β 0.067 | 4E-26 | PubMed |
| Household income | A | β 0.017 | 1E-17 | PubMed |
| Occupational creativity | A | β 0.025 | 2E-17 | PubMed |
| Refractive error | — | — | 2E-15 | PubMed |
| Monounsaturated fatty acids to total fatty acids percentage | A | β 0.01 | 2E-13 | PubMed |
| Autism spectrum disorder vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) | — | β 0.021 | 2E-11 | PubMed |
| Anorexia nervosa vs Tourette's syndrome and other tic disorders (ordinary least squares (OLS)) | — | β 0.024 | 7E-11 | PubMed |
| Serum total protein levels | A | β 0.014 | 1E-10 | PubMed |
| Cognitive traits (MTAG) | — | — | 2E-10 | PubMed |
| Educational attainment | — | β 0.026 | 1E-9 | PubMed |
| Regular attendance at a pub or social club | C | β 0.005 | 8E-9 | PubMed |
| Tourette syndrome | C | OR 1.13 | 3E-7 | PubMed |
| Word reading | A | β 0.04 | 7E-7 | PubMed |
Sources
- dbSNP: rs1906252 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies