RS1800795 IL6

Health Risk Chr 7:22727025 snv 5 prime UTR variant

Upload your DNA to see your genotype for this variant.

What This Variant Does

"rs1800795 is a SNP in the promoter of the interleukin-6 IL6 gene, affecting the levels made of this ..."

Associated Conditions

Crohn disease-associated growth failure

susceptibility to

Kaposi sarcoma

Diabetes mellitus type 2

Diabetes mellitus

type 1

Cholangiocarcinoma

Crohn disease-associated growth failure

susceptibility to

Kaposi sarcoma

Diabetes mellitus type 2

Diabetes mellitus

type 1

Cholangiocarcinoma

GWAS Studies (5)

Trait	Risk Allele	OR / Beta	P-value	Study
Pulse pressure	T	OR: 0.18	2E-25	PubMed
Pulse pressure	G	OR: 0.18	2E-19	PubMed
Pulse pressure	C	OR: 0.17	7E-12	PubMed
Systolic blood pressure	G	OR: 0.19	5E-11	PubMed
Cerebrospinal fluid clusterin levels in APOEe4- carriers	—	OR: 0.38	7E-8	PubMed

Population Frequencies

gnomAD ALL

65.2%

1kG AFR

98.2%

1kG ALL

85.9%

1kG AMR

18.4%

1kG EAS

99.9%

1kG EUR

58.4%

1kG SAS

86.1%