RS1799884 Unknown gene
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What This Variant Does
"rs1799884, known also as the -30 SNP of the GCK gene, has been associated with type-2 diabetes. This..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Glucose (fasting status unknown, mean, inv-norm transformed) | C | β: 0.094 | 5E-162 | PubMed |
| Glucose (fasting status unknown, minimum, inv-norm transformed) | C | β: 0.069 | 4E-134 | PubMed |
| Glucose (fasting status unknown, maximum, inv-norm transformed) | C | β: 0.065 | 7E-84 | PubMed |
| Abnormal glucose (PheCode 250.4) | C | OR: 0.11 | 1E-68 | PubMed |
| Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) | C | β: 0.065 | 1E-66 | PubMed |
| Hemoglobin A1c (HbA1c, mean, inv-norm transformed) | C | β: 0.063 | 1E-58 | PubMed |
| Hemoglobin A1c (HbA1c, maximum, inv-norm transformed) | C | β: 0.059 | 1E-53 | PubMed |
| Impaired fasting glucose (PheCode 250.41) | C | OR: 0.12 | 5E-48 | PubMed |
| Glucose (fasting status unknown, mean, inv-norm transformed) | C | β: 0.084 | 5E-46 | PubMed |
| Glucose (fasting status unknown, minimum, inv-norm transformed) | C | β: 0.062 | 3E-29 | PubMed |
| Fasting glucose | T | β: 0.06 | 4E-28 | PubMed |
| Fasting blood glucose | T | OR: 0.14 | 8E-27 | PubMed |
| Glucose (fasting status unknown, maximum, inv-norm transformed) | C | β: 0.062 | 4E-26 | PubMed |
| Fasting blood glucose | — | OR: 0.12 | 2E-25 | PubMed |
| Glucose (fasting status unknown, mean, inv-norm transformed) | C | β: 0.074 | 4E-24 | PubMed |
| Glycated hemoglobin levels | T | β: 0.033 | 2E-23 | PubMed |
| Glycated hemoglobin levels | T | OR: 0.12 | 2E-22 | PubMed |
| Hemoglobin A1c levels | T | OR: 0.11 | 3E-22 | PubMed |
| Multi-trait sum score | — | — | 8E-21 | PubMed |
| Glycated hemoglobin levels | T | β: 0.04 | 1E-20 | PubMed |