Genetic variant

rs17855739

rs17855739 is a single-letter difference in human DNA, on chromosome 19. Carrying it does not, on its own, mean you have or will develop any condition.

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What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs17855739 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs17855739, if your test read this position.

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Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

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What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
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This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs17855739
Position
chr19:5831829

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
Alpha-(1,3)-fucosyltransferase 5 levels — OR 0.71 7E-108 PubMed
Lactoperoxidase levels — OR 0.62 2E-96 PubMed
SELE protein levels T β 0.073 6E-61 PubMed
Aspartate aminotransferase levels T β 0.045 5E-43 PubMed
KLK13 protein levels T OR 0.16 4E-35 PubMed
Aspartate aminotransferase (AST, minimum, inv-norm transformed) C β 0.049 1E-29 PubMed
Aspartate aminotransferase (AST, mean, inv-norm transformed) C β 0.047 1E-27 PubMed
Aspartate aminotransferase levels (UKB data field 30650) T β 0.05 2E-26 PubMed
KLK12 protein levels T OR 0.14 2E-24 PubMed
E-selectin levels T OR 0.14 4E-24 PubMed
Aspartate aminotransferase levels C OR 10.1 8E-24 PubMed
Aspartate aminotransferase levels T β 0.045 1E-22 PubMed
Aspartate aminotransferase (AST, maximum, inv-norm transformed) C β 0.037 3E-19 PubMed
Lactoperoxidase level in Chronic kidney disease with hypertension and no diabetes (4801_13) T OR 0.68 4E-17 PubMed
Vitamin B-complex deficiencies (PheCode 261.2) C OR 0.15 4E-16 PubMed
B4GAT1 protein levels T β 0.1 7E-16 PubMed
Age-related macular degeneration or COVID-19 infection (MTAG) — OR 0.16 9E-16 PubMed
Age-related macular degeneration or COVID-19 hospitalization (MTAG) — OR 0.15 1E-15 PubMed
Age-related macular degeneration or COVID-19 critical illness (MTAG) — OR 0.15 2E-15 PubMed
Aspartate aminotransferase (AST, minimum, inv-norm transformed) C β 0.039 2E-14 PubMed

Sources