Genetic variant
rs13702
rs13702 is a single-letter difference in human DNA, on chromosome 8. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs13702 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs13702, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs13702
- Position
- chr8:19966981
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Triglycerides | T | OR 0.12 | 5E-177 | PubMed |
| Free cholesterol in very large HDL | C | β 0.077 | 8E-146 | PubMed |
| Ratio of apolipoprotein B to apolipoprotein A1 levels | C | β 0.06 | 2E-140 | PubMed |
| High density lipoprotein cholesterol levels | T | OR 0.11 | 1E-139 | PubMed |
| HDL cholesterol levels x short total sleep time interaction (2df test) | — | β 0.024 | 2E-112 | PubMed |
| Phospholipids to Total Lipids in Very Large VLDL percentage | C | β 0.05 | 7E-93 | PubMed |
| Ratio of apolipoprotein B to apolipoprotein A1 levels | T | β 0.073 | 1E-58 | PubMed |
| Concentration of small LDL particles | C | β 0.03 | 4E-49 | PubMed |
| LDLR protein levels | C | β 0.079 | 3E-48 | PubMed |
| Apolipoprotein B to apolipoprotein A1 ratio (UKB data field 23441) | C | β 0.075 | 1E-47 | PubMed |
| Free cholesterol in very large HDL | C | β 0.046 | 2E-43 | PubMed |
| HDL cholesterol levels | C | OR 0.17 | 5E-41 | PubMed |
| High density lipoprotein cholesterol levels | — | OR 0.11 | 9E-41 | PubMed |
| Apolipoprotein B levels | T | β 0.03 | 1E-38 | PubMed |
| Cholesteryl Esters in Small LDL | C | β 0.03 | 4E-37 | PubMed |
| Total lipids in very small VLDL | T | β 0.057 | 1E-36 | PubMed |
| Free Cholesterol to Total Lipids in Large VLDL percentage | C | β 0.03 | 3E-36 | PubMed |
| Phospholipids to total lipids ratio in very large VLDL | T | β 0.052 | 4E-30 | PubMed |
| Triacylglyceride levels | C | OR 0.16 | 1E-29 | PubMed |
| Triglycerides to Total Lipids in Large VLDL percentage | C | β 0.02 | 2E-27 | PubMed |
Sources
- dbSNP: rs13702 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies