Genetic variant
rs13179413
rs13179413 is a single-letter difference in human DNA, on chromosome 5. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs13179413 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
Duffy antigen receptor genetic variant and the association with Interleukin 8 levels
From SNPedia
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs13179413, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs13179413
- Position
- chr5:56572270
Genome-wide association studies (15)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Cholesteryl Esters to Total Lipids in IDL percentage | T | β 0.02 | 2E-29 | PubMed |
| Haematocrit percentage (UKB data field 30030) | T | β 0.021 | 3E-28 | PubMed |
| Impedance of arm left (UKB data field 23110) | T | β 0.013 | 2E-19 | PubMed |
| Hypertension (confirmatory factor analysis Factor 12) | — | — | 4E-17 | PubMed |
| Cardiovascular disease | — | — | 2E-16 | PubMed |
| Systolic blood pressure | T | OR 0.22 | 6E-15 | PubMed |
| Impedance of whole body (UKB data field 23106) | T | β 0.012 | 6E-15 | PubMed |
| Diastolic blood pressure | T | OR 0.13 | 2E-14 | PubMed |
| Systolic blood pressure | T | OR 0.2 | 6E-13 | PubMed |
| Systolic blood pressure | — | — | 3E-11 | PubMed |
| Ratio of linoleic acid to total fatty acids | C | β 0.029 | 6E-11 | PubMed |
| Free cholesterol to total lipids in very large VLDL percentage (UKB data field 23587) | T | β 0.033 | 2E-10 | PubMed |
| Diastolic blood pressure | — | β 0.014 | 4E-10 | PubMed |
| Heart failure (MTAG) | T | OR 6.03 | 2E-9 | PubMed |
| Pulse pressure | T | β 0.089 | 9E-6 | PubMed |
Sources
- dbSNP: rs13179413 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies