RS12670798 Unknown gene
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What This Variant Does
"per the 23andMe blog, the minor allele of this SNP (C) was associated with increased cholesterol and..."
GWAS Studies (17)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Phospholipids to Total Lipids in Large HDL percentage | C | β: 0.02 | 4E-23 | PubMed |
| Cholesterol esters in IDL | T | β: 0.044 | 7E-23 | PubMed |
| Cholesterol esters in medium LDL | T | β: 0.041 | 9E-20 | PubMed |
| Cholesterol, total | C | β: 0.036 | 1E-16 | PubMed |
| Total cholesterol levels | T | β: 0.036 | 5E-15 | PubMed |
| LDL cholesterol | C | β: 0.034 | 5E-14 | PubMed |
| LDL cholesterol levels | T | β: 0.034 | 2E-12 | PubMed |
| Free Cholesterol to Total Lipids in Very Small VLDL percentage | C | β: 0.02 | 3E-11 | PubMed |
| Cholesteryl esters to total lipids ratio in chylomicrons and extremely large VLDL | T | β: 0.031 | 2E-10 | PubMed |
| LDL cholesterol | C | OR: 1.26 | 7E-10 | PubMed |
| Cholesterol, total | T | OR: 1.7 | 7E-10 | PubMed |
| LDL cholesterol | G | β: 0.09 | 6E-9 | PubMed |
| Total cholesterol levels | T | β: 0.026 | 6E-8 | PubMed |
| LDL cholesterol levels | T | OR: 1.09 | 5E-7 | PubMed |
| Triglycerides | T | β: 0.022 | 6E-7 | PubMed |
| Cholesterol, total | G | β: 0.06 | 9E-7 | PubMed |
| Low density lipoprotein cholesterol levels | T | β: 0.023 | 3E-6 | PubMed |