RS12459419 Unknown gene
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What This Variant Does
"Clinical Significance of CD33 Nonsynonymous Single-Nucleotide Polymorphisms in Pediatric Patients with Acute Myeloid Leukemia Treated with Gemtuzumab-Ozogamicin-Containing Chemotherapy"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Myeloid cell surface antigen CD33 levels | T | OR: 0.94 | 3E-1638 | PubMed |
| Myeloid cell surface antigen CD33 levels (CD33.3166.92.1) | T | OR: 0.94 | 9E-445 | PubMed |
| Myeloid cell surface antigen CD33 levels | T | OR: 1.02 | 1E-430 | PubMed |
| Myeloid cell surface antigen CD33 levels | T | OR: 1.23 | 1E-291 | PubMed |
| Myeloid cell surface antigen CD33 levels | T | OR: 1.13 | 3E-165 | PubMed |
| Protein quantitative trait loci | — | — | 2E-77 | PubMed |
| white blood cell count (WBC, mean, inv-norm transformed) | C | β: 0.043 | 4E-48 | PubMed |
| Platelet count | T | β: 0.026 | 6E-44 | PubMed |
| White blood cell count | T | β: 0.027 | 3E-43 | PubMed |
| White blood cell count | T | — | 4E-42 | PubMed |
| Platelet crit (UKB data field 30090) | T | β: 0.023 | 1E-35 | PubMed |
| platelet count (mean, inv-norm transformed) | C | β: 0.037 | 5E-35 | PubMed |
| white blood cell count (WBC, minimum, inv-norm transformed) | C | β: 0.036 | 5E-35 | PubMed |
| Glycated haemoglobin HbA1c levels (UKB data field 30750) | T | β: 0.023 | 2E-34 | PubMed |
| White blood cell count | T | β: 0.02 | 2E-33 | PubMed |
| Lymphocyte count | T | β: 0.024 | 8E-33 | PubMed |
| White blood cell count | — | — | 1E-32 | PubMed |
| Protein p13 MTCP-1 protein levels (SomaScan ID:3166-92) | T | OR: 1.15 | 1E-31 | PubMed |
| Lymphocyte count | T | — | 4E-30 | PubMed |
| Platelet count (UKB data field 30080) | T | β: 0.021 | 6E-30 | PubMed |