RS12459249 Unknown gene
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What This Variant Does
"Genome-wide association of the laboratory-based nicotine metabolite ratio in three ancestries."
GWAS Studies (8)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Nicotine metabolite ratio in current smokers | C | OR: 0.59 | 1E-39 | PubMed |
| Alanine transaminase (ALT, maximum, inv-norm transformed) | T | β: 0.022 | 3E-16 | PubMed |
| Alanine transaminase (ALT, mean, inv-norm transformed) | T | β: 0.021 | 4E-15 | PubMed |
| Smoking status (current vs mixed) | C | OR: 0.94 | 8E-15 | PubMed |
| Chronic bronchitis (PheCode 496.2) | T | β: 0.075 | 2E-14 | PubMed |
| Cigarettes smoked per day (past) | T | β: 0.033 | 1E-11 | PubMed |
| Coffee intake (standard GWA) | T | β: 0.039 | 4E-10 | PubMed |
| Chronic obstructive pulmonary disease | C | OR: 1.1 | 3E-8 | PubMed |