RS12193446 Unknown gene
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What This Variant Does
"risk of nearsightedness in people with European ancestry http://www.plosgenetics.org/article/info:do..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Spherical equivalent | G | OR: 0.42 | 4E-107 | PubMed |
| Myopia | — | OR: 1.3 | 5E-102 | PubMed |
| Myopia (age of diagnosis) | A | OR: 0.25 | 4E-86 | PubMed |
| Refractive error (autorefraction measured) | A | OR: 0.41 | 7E-85 | PubMed |
| Spherical equivalent or myopia (age of diagnosis) | A | OR: 19.43 | 4E-84 | PubMed |
| Myopia | G | OR: 0.33 | 6E-62 | PubMed |
| Age-related eyesight deterioration (confirmatory factor analysis Factor 27) | — | — | 1E-57 | PubMed |
| Myopia (PheCode 367.1) | A | OR: 0.16 | 1E-43 | PubMed |
| Myopia (PheCode 367.1) | A | OR: 0.15 | 1E-33 | PubMed |
| Ocular disease | — | — | 1E-33 | PubMed |
| Low myopia vs hyperopia | — | OR: 0.41 | 2E-32 | PubMed |
| Hypermetropia (PheCode 367.8) | A | OR: 0.11 | 3E-29 | PubMed |
| Age started wearing glasses (UKB data field 2217) | G | β: 0.038 | 3E-27 | PubMed |
| Hypermetropia (PheCode 367.8) | A | OR: 0.12 | 4E-25 | PubMed |
| High myopia | A | OR: 1.72 | 7E-23 | PubMed |
| Spherical equivalent (joint analysis main effects and education interaction) | A | — | 1E-21 | PubMed |
| High myopia | — | OR: 0.49 | 5E-20 | PubMed |
| Spherical equivalent | A | OR: 0.21 | 6E-16 | PubMed |
| Hyperopia | — | OR: 0.21 | 3E-14 | PubMed |
| Axial length | G | OR: 0.17 | 5E-14 | PubMed |