RS119468010 MPO
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What This Variant Does
"[OMIM:?]
Associated Conditions
Myeloperoxidase deficiency
Alzheimer disease type 1
MPO-related disorder
Myeloperoxidase deficiency
Alzheimer disease type 1
MPO-related disorder
GWAS Studies (10)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| MPO protein levels | A | OR: 1.6 | 4E-263 | PubMed |
| Neutrophil side scatter | A | OR: 0.99 | 3E-64 | PubMed |
| Neutrophil side fluorescence | A | OR: 0.55 | 5E-21 | PubMed |
| TNFRSF10C protein levels | A | OR: 0.3 | 1E-18 | PubMed |
| Neutrophil count | A | OR: 0.16 | 9E-18 | PubMed |
| White blood cell count | A | OR: 0.15 | 2E-16 | PubMed |
| Neutrophill count (UKB data field 30140) | A | OR: 0.12 | 5E-14 | PubMed |
| Neutrophil count | — | OR: 0.13 | 8E-14 | PubMed |
| CEACAM8 protein levels | A | OR: 0.32 | 2E-13 | PubMed |
| White blood cell count | — | OR: 0.12 | 7E-13 | PubMed |
Population Frequencies
gnomAD ALL
99.7%
1kG AFR
100%
1kG ALL
100%
1kG AMR
100%
1kG EAS
100%
1kG EUR
0.1%
1kG SAS
99.9%
Other Variants in MPO