RS11874392 Unknown gene
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What This Variant Does
"Genetic Variations in SMAD7 Are Associated with Colorectal Cancer Risk in the Colon Cancer Family Registry"
GWAS Studies (15)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Colorectal cancer or advanced adenoma | A | OR: 1.17 | 4E-74 | PubMed |
| Benign neoplasm of colon (PheCode 208) | A | β: 0.075 | 2E-57 | PubMed |
| Colorectal cancer | — | OR: 0.85 | 4E-37 | PubMed |
| Colorectal cancer | T | OR: 0.16 | 6E-36 | PubMed |
| Colon polyp | T | OR: 0.1 | 5E-28 | PubMed |
| Colorectal cancer | T | OR: 0.18 | 6E-25 | PubMed |
| Colorectal cancer | T | OR: 0.85 | 1E-20 | PubMed |
| Colorectal cancer | T | OR: 0.84 | 2E-20 | PubMed |
| Early onset colorectal cancer | A | OR: 1.19 | 1E-18 | PubMed |
| Colorectal cancer | — | OR: 0.85 | 3E-18 | PubMed |
| Colorectal cancer | T | OR: 0.84 | 4E-18 | PubMed |
| Colorectal cancer (PheCode 153) | A | β: 0.098 | 1E-13 | PubMed |
| Colon cancer (PheCode 153.2) | A | OR: 0.11 | 4E-13 | PubMed |
| Colon cancer (PheCode 153.2) | A | OR: 0.1 | 2E-11 | PubMed |
| Colorectal cancer | A | OR: 1.27 | 7E-8 | PubMed |