RS11571833 Unknown gene
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What This Variant Does
"This SNP, a variant in the BRCA2 gene, is 1 of 25 SNPs reported to represent independently minor, bu...
GWAS Studies (18)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Lung cancer (conditioned on cigarettes per day) | A | OR: 0.64 | 1E-20 | PubMed |
| Lung cancer | T | OR: 2.47 | 5E-20 | PubMed |
| Lung cancer | T | OR: 1.6 | 6E-16 | PubMed |
| Breast cancer | T | OR: 1.35 | 3E-15 | PubMed |
| Breast cancer (estrogen-receptor negative) | T | OR: 1.58 | 2E-13 | PubMed |
| Cancer | T | OR: 1.6 | 8E-12 | PubMed |
| Illnesses of father: Lung cancer (UKB data field 20107_3) | T | OR: 0.29 | 8E-12 | PubMed |
| Small cell lung carcinoma | T | OR: 2.19 | 3E-8 | PubMed |
| Multiple myeloma | T | OR: 1.57 | 3E-8 | PubMed |
| Squamous cell lung carcinoma | T | β: 0.5 | 5E-8 | PubMed |
| Breast cancer | T | OR: 1.26 | 5E-8 | PubMed |
| Lung cancer in ever smokers | T | OR: 1.49 | 6E-8 | PubMed |
| Breast cancer | T | OR: 1.27 | 6E-7 | PubMed |
| Cutaneous squamous cell carcinoma | — | OR: 0.36 | 1E-6 | PubMed |
| Breast cancer | T | OR: 1.27 | 2E-6 | PubMed |
| Non-small cell lung cancer | T | OR: 0.67 | 5E-6 | PubMed |
| Breast cancer (estrogen-receptor negative) | — | OR: 1.32 | 6E-6 | PubMed |
| Breast cancer | T | OR: 1.52 | 6E-6 | PubMed |