RS11554159 Unknown gene
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What This Variant Does
"Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor. The effect of si..."
GWAS Studies (14)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| LGALS9/SIGLEC1 protein level ratio | — | OR: 0.14 | 8E-71 | PubMed |
| CSF1/SIGLEC1 protein level ratio | — | OR: 0.13 | 6E-69 | PubMed |
| CD163/SIGLEC1 protein level ratio | — | OR: 0.13 | 2E-66 | PubMed |
| MARCO/SIGLEC1 protein level ratio | — | OR: 0.12 | 5E-56 | PubMed |
| SIGLEC1 protein levels | A | β: 0.082 | 4E-45 | PubMed |
| SSC-A on monocyte | A | OR: 0.37 | 3E-36 | PubMed |
| SSC-A on CD14+ monocyte | A | OR: 0.3 | 2E-25 | PubMed |
| Multiple sclerosis | G | OR: 1.15 | 2E-24 | PubMed |
| CD164/CD99 protein level ratio | — | β: 0.069 | 4E-23 | PubMed |
| Alkaline phosphatase (UKB data field 30610) | A | β: 0.018 | 1E-18 | PubMed |
| Waist-to-hip ratio adjusted for BMI (additive genetic model) | A | β: 0.023 | 2E-11 | PubMed |
| Waist-to-hip ratio adjusted for BMI (additive genetic model) | A | β: 0.022 | 4E-11 | PubMed |
| Waist-to-hip ratio adjusted for BMI (additive genetic model) | A | β: 0.015 | 3E-10 | PubMed |
| Waist-to-hip ratio adjusted for BMI (additive genetic model) | A | β: 0.016 | 6E-10 | PubMed |