RS1133400 Unknown gene
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What This Variant Does
"A distinct and replicable variant of the squamous cell carcinoma gene inositol polyphosphate-5-phosphatase modifies the susceptibility of arsenic-associated skin lesions in Bangladesh"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Sex hormone-binding globulin levels and heel estimated bone mineral density | — | — | 2E-51 | PubMed |
| Heel bone mineral density | A | β: 0.031 | 1E-43 | PubMed |
| Heel bone mineral density | — | — | 4E-40 | PubMed |
| Heel bone mineral density | — | β: 0.029 | 1E-32 | PubMed |
| Systolic blood pressure | A | OR: 0.25 | 4E-20 | PubMed |
| Systolic blood pressure | G | OR: 0.26 | 1E-18 | PubMed |
| Systolic blood pressure | A | OR: 0.26 | 7E-18 | PubMed |
| Systolic blood pressure | A | β: 0.014 | 4E-16 | PubMed |
| Systolic blood pressure | A | OR: 0.25 | 1E-14 | PubMed |
| Systolic blood pressure (MTAG) | G | β: 0.016 | 3E-14 | PubMed |
| Pulse pressure | A | OR: 0.14 | 4E-14 | PubMed |
| Estimated glomerular filtration rate (creatinine, cystatin c) | G | β: 0.018 | 4E-13 | PubMed |
| Pulse pressure | G | OR: 0.15 | 1E-12 | PubMed |
| Metabolic syndrome | — | β: 0.011 | 2E-12 | PubMed |
| Serum urate levels | A | β: 0.02 | 3E-12 | PubMed |
| Triglyceride levels | — | — | 1E-11 | PubMed |
| Hematocrit | G | β: 0.013 | 2E-11 | PubMed |
| Systolic blood pressure | — | — | 3E-11 | PubMed |
| Systolic blood pressure | A | OR: 0.3 | 3E-11 | PubMed |
| Diastolic blood pressure | A | β: 0.012 | 4E-11 | PubMed |