Genetic variant
rs11264341
rs11264341 is a single-letter difference in human DNA, on chromosome 1. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs11264341 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs11264341, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs11264341
- Position
- chr1:155179017
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Serum uric acid levels | T | β 0.035 | 2E-82 | PubMed |
| Urea levels | T | β 0.043 | 1E-70 | PubMed |
| Urate levels | T | β 0.042 | 8E-69 | PubMed |
| Gout | T | OR 0.9 | 3E-64 | PubMed |
| Gamma glutamyl transferase levels | T | β 0.041 | 1E-63 | PubMed |
| Gout and other crystal arthrop (PheCode 274) | C | OR 0.1 | 2E-53 | PubMed |
| Gout (PheCode 274.1) | C | OR 0.1 | 2E-52 | PubMed |
| Gout (PheCode 274.1) | C | β 0.096 | 4E-31 | PubMed |
| Takes medication for gout? | C | OR 0.11 | 2E-25 | PubMed |
| Takes medication for gout? | C | β 0.1 | 3E-24 | PubMed |
| Calcium levels | T | β 0.026 | 3E-24 | PubMed |
| Alanine aminotransferase levels | T | β 0.024 | 4E-23 | PubMed |
| Aspartate aminotransferase levels | T | β 0.024 | 2E-22 | PubMed |
| Serum urate level in bendroflumethiazide treated hypertension | — | β 0.043 | 2E-19 | PubMed |
| Urate levels | T | β 0.05 | 6E-19 | PubMed |
| Urate levels | C | β 0.049 | 4E-18 | PubMed |
| Serum uric acid levels | T | β 0.04 | 8E-18 | PubMed |
| ICD10 K31.7: Polyp of stomach and duodenum | — | OR 1.17 | 6E-17 | PubMed |
| Serum phosphate levels | T | β 0.02 | 2E-15 | PubMed |
| LAMP3/MSLN protein level ratio | — | β 0.055 | 5E-15 | PubMed |
Sources
- dbSNP: rs11264341 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies