Genetic variant
rs10982156
rs10982156 is a single-letter difference in human DNA, on chromosome 9. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs10982156 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs10982156, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs10982156
- Position
- chr9:114325784
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| F10 protein levels | A | OR 0.36 | 1E-220 | PubMed |
| Glycoprotein acetyls levels | A | OR 0.13 | 1E-206 | PubMed |
| PROS1 protein levels | A | OR 0.34 | 4E-189 | PubMed |
| Coagulation factor Xa levels | A | OR 0.49 | 8E-72 | PubMed |
| CLEC1A protein levels | A | OR 0.18 | 2E-61 | PubMed |
| Serum levels of protein F10 | A | OR 0.46 | 9E-51 | PubMed |
| GFRA1 protein levels | A | OR 0.15 | 5E-49 | PubMed |
| Serum levels of protein F10 | A | OR 0.45 | 3E-47 | PubMed |
| TNFRSF1A protein levels | A | OR 0.13 | 2E-39 | PubMed |
| S100A12 protein levels | A | OR 0.12 | 5E-25 | PubMed |
| MAN1A2 protein levels | A | β 0.099 | 2E-21 | PubMed |
| Free testosterone levels | — | β 0.059 | 2E-17 | PubMed |
| TNC protein levels | A | β 0.086 | 1E-16 | PubMed |
| Serum levels of protein SPINK2 | A | OR 0.25 | 1E-15 | PubMed |
| F2 protein levels | A | β 0.099 | 2E-15 | PubMed |
| Bioavailable testosterone levels | A | β 0.048 | 5E-14 | PubMed |
| GPNMB protein levels | A | β 0.082 | 2E-13 | PubMed |
| Phospholipids to Total Lipids in Small HDL percentage | A | β 0.03 | 4E-13 | PubMed |
| Serum levels of protein TFPI | A | OR 0.22 | 4E-12 | PubMed |
| NHLRC3 protein levels | A | β 0.076 | 7E-12 | PubMed |
Sources
- dbSNP: rs10982156 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies