Genetic variant
rs1061808
rs1061808 is a single-letter difference in human DNA, on chromosome 6. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs1061808 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs1061808, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs1061808
- Position
- chr6:32168770
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Saturated fatty acids to total fatty acids percentage | G | β 0.03 | 4E-52 | PubMed |
| 1,2-dipalmitoyl-gpc (16:0/16:0) levels | G | OR 0.2 | 2E-37 | PubMed |
| Tenascin-X levels (TNXB.5698.60.3) | G | OR 0.32 | 8E-37 | PubMed |
| Ratio of saturated fatty acids to total fatty acids | T | β 0.05 | 6E-34 | PubMed |
| Triacylglycerol (50:2) [NL-18:2] levels | G | OR 0.27 | 1E-32 | PubMed |
| Average diameter for LDL particles | G | β 0.02 | 5E-31 | PubMed |
| Triacylglycerol (50:1) [NL-18:1] levels | G | OR 0.26 | 2E-30 | PubMed |
| Monounsaturated fatty acids to total fatty acids percentage | T | — | 8E-28 | PubMed |
| Pulse pressure | T | OR 0.28 | 7E-24 | PubMed |
| Pulse pressure | T | OR 0.25 | 1E-23 | PubMed |
| 1,2-dipalmitoyl-gpc (16:0/16:0) levels | T | OR 0.1 | 3E-23 | PubMed |
| Pulse pressure | G | β 0.018 | 1E-22 | PubMed |
| 1,2-dipalmitoyl-gpc (16:0/16:0) levels | T | OR 0.15 | 4E-22 | PubMed |
| Saturated fatty acids to total fatty acids percentage | T | — | 2E-20 | PubMed |
| Monounsaturated fatty acids to total fatty acids percentage | T | — | 4E-20 | PubMed |
| Plasma 1,2-dipalmitoyl-GPC (16:0/16:0) levels in chronic kidney disease | G | β 0.047 | 6E-19 | PubMed |
| Phosphatidylcholine_32:0_[M+H]1+/Phosphatidylethanolamine_35:0_[M+H]1+/Phosphatidate_37:1_[M+NH4]1+ levels | T | β 0.096 | 1E-15 | PubMed |
| Triacylglycerol (50:2) [NL-18:2] levels | G | OR 0.18 | 2E-15 | PubMed |
| Triacylglycerol (50:1) [NL-18:1] levels | G | OR 0.18 | 9E-15 | PubMed |
| Phospholipid levels (plasma) | — | OR 0.9 | 8E-10 | PubMed |
Sources
- dbSNP: rs1061808 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies