RS10033900 Unknown gene
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What This Variant Does
"Plasma complement components and activation fragments: associations with age-related macular degener..."
GWAS Studies (14)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| CFI protein levels | C | OR: 0.17 | 4E-210 | PubMed |
| Serum levels of protein CFI | C | OR: 0.28 | 8E-54 | PubMed |
| Blood protein levels | T | OR: 0.3 | 4E-34 | PubMed |
| Complement factor I levels | T | OR: 0.24 | 4E-20 | PubMed |
| Age-related macular degeneration or COVID-19 infection (MTAG) | — | β: 0.06 | 2E-18 | PubMed |
| Age-related macular degeneration or COVID-19 hospitalization (MTAG) | — | β: 0.06 | 3E-18 | PubMed |
| Age-related macular degeneration or COVID-19 critical illness (MTAG) | — | β: 0.06 | 4E-18 | PubMed |
| Advanced age-related macular degeneration | — | OR: 1.15 | 5E-17 | PubMed |
| CFP protein levels | C | β: 0.042 | 3E-15 | PubMed |
| CFB protein levels | C | β: 0.036 | 8E-12 | PubMed |
| Age-related macular degeneration | T | OR: 1.18 | 4E-10 | PubMed |
| Age-related macular degeneration (choroidal neovascularisation) | T | OR: 1.31 | 6E-9 | PubMed |
| Age-related macular degeneration | — | — | 9E-9 | PubMed |
| Age-related macular degeneration (geographic atrophy) | T | OR: 1.32 | 4E-6 | PubMed |