RS9934438 VKORC1

Drug Response Chr 16:31093556 snv intron variant

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What This Variant Does

"risk of aortic calcification was calculated, adjusted for potential confounders. The T allele freque...

Associated Conditions

Warfarin response

warfarin response - Dosage

acenocoumarol response - Dosage

phenprocoumon response - Dosage

Warfarin response

warfarin response - Dosage

acenocoumarol response - Dosage

phenprocoumon response - Dosage

GWAS Studies (2)

Trait	Risk Allele	OR / Beta	P-value	Study
Stable warfarin dose	—	OR: 2.34	8E-20	PubMed
Warfarin dose variability	A	OR: 0.16	8E-15	PubMed

Population Frequencies

gnomAD ALL

62%

1kG AFR

5.4%

1kG ALL

35.6%

1kG AMR

58.8%

1kG EAS

11.5%

1kG EUR

38.8%

1kG SAS

85.5%

Other Variants in VKORC1