Genetic variant
rs9920
rs9920 is a single-letter difference in human DNA, on chromosome 7. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs9920 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
Genetic Variation in Caveolin-1 Correlates With Long-Term Pancreas Transplant Function
From SNPedia
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs9920, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs9920
- Position
- chr7:116560038
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| High light scatter reticulocyte percentage of red cells | C | β 0.043 | 1E-32 | PubMed |
| High light scatter reticulocyte count | C | β 0.04 | 1E-28 | PubMed |
| Reticulocyte fraction of red cells | C | β 0.04 | 2E-28 | PubMed |
| High light scatter reticulocyte percentage (UKB data field 30290) | C | β 0.034 | 5E-28 | PubMed |
| Reticulocyte percentage (UKB data field 30240) | C | β 0.033 | 7E-26 | PubMed |
| Reticulocyte fraction of red cells | C | β 0.06 | 1E-24 | PubMed |
| Reticulocyte count | C | β 0.037 | 1E-23 | PubMed |
| High light scatter reticulocyte percentage of red cells | C | β 0.057 | 6E-22 | PubMed |
| Lymphocyte count | C | β 0.029 | 2E-21 | PubMed |
| Lymphocyte count | C | β 0.034 | 2E-21 | PubMed |
| Reticulocyte count (UKB data field 30250) | C | β 0.029 | 4E-21 | PubMed |
| Reticulocyte count | C | β 0.055 | 1E-20 | PubMed |
| High light scatter reticulocyte count | C | β 0.053 | 1E-19 | PubMed |
| Lymphocyte count | C | — | 2E-18 | PubMed |
| Lymphocyte count (UKB data field 30120) | C | β 0.026 | 1E-17 | PubMed |
| Immature fraction of reticulocytes | C | β 0.029 | 7E-15 | PubMed |
| Immature reticulocyte fraction (UKB data field 30280) | C | β 0.024 | 3E-13 | PubMed |
| Lymphocyte percentage of white cells | C | β 0.026 | 5E-13 | PubMed |
| Lymphocyte-to-monocyte ratio | T | — | 1E-11 | PubMed |
| Monocyte percentage of white cells | C | β 0.023 | 3E-10 | PubMed |
Sources
- dbSNP: rs9920 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies