Genetic variant
rs9895661
rs9895661 is a single-letter difference in human DNA, on chromosome 17. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs9895661 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs9895661, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs9895661
- Position
- chr17:61379228
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Creatinine levels | T | β 0.051 | 1E-308 | PubMed |
| Estimated glomerular filtration rate (creatinine) | C | β 0.008 | 1E-169 | PubMed |
| Serum creatinine levels | T | β 0.044 | 2E-117 | PubMed |
| Creatinine levels (UKB data field 30700) | T | β 0.047 | 7E-113 | PubMed |
| Estimated glomerular filtration rate | T | β 0.007 | 1E-106 | PubMed |
| Creatinine levels | T | β 0.066 | 3E-100 | PubMed |
| Estimated glomerular filtration rate | T | β 0.066 | 4E-98 | PubMed |
| Creatinine levels | C | β 0.055 | 4E-92 | PubMed |
| creatinine (mean, inv-norm transformed) | C | β 0.06 | 7E-80 | PubMed |
| estimated glomerular filtration rate (eGFR, mean, inv-norm transformed) | C | β 0.059 | 3E-79 | PubMed |
| Uric acid levels | C | β 0.056 | 7E-78 | PubMed |
| creatinine (minimum, inv-norm transformed) | C | β 0.058 | 4E-73 | PubMed |
| estimated glomerular filtration rate (eGFR, maximum, inv-norm transformed) | C | β 0.056 | 9E-70 | PubMed |
| Hemoglobin levels | T | β 0.023 | 4E-65 | PubMed |
| Serum urate levels | T | β 0.046 | 3E-63 | PubMed |
| creatinine (maximum, inv-norm transformed) | C | β 0.052 | 1E-60 | PubMed |
| estimated glomerular filtration rate (eGFR, mean, inv-norm transformed) | C | β 0.047 | 7E-59 | PubMed |
| estimated glomerular filtration rate (eGFR, minimum, inv-norm transformed) | C | β 0.049 | 4E-58 | PubMed |
| creatinine (mean, inv-norm transformed) | C | β 0.043 | 5E-58 | PubMed |
| Estimated glomerular filtration rate | T | β 0.007 | 1E-57 | PubMed |
Sources
- dbSNP: rs9895661 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies