RS8040868 Unknown gene
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What This Variant Does
"[GWAS:Pulmonary function (interaction)]"
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Chronic lung diseases including COPD, Emphysema and Bronchitis | T | OR: 0.13 | 3E-73 | PubMed |
| Chronic obstructive pulmonary disease | C | β: 0.097 | 7E-60 | PubMed |
| Chronic lung diseases including COPD, Emphysema and Bronchitis | T | OR: 0.12 | 6E-56 | PubMed |
| Squamous cell lung carcinoma | C | OR: 1.29 | 3E-41 | PubMed |
| Chronic obstructive pulmonary disease x current smoker interaction (2df) | C | — | 8E-24 | PubMed |
| Cigarettes smoked per day (past) | C | β: 0.044 | 2E-20 | PubMed |
| Chronic obstructive pulmonary disease in current smokers | C | OR: 1.3 | 7E-20 | PubMed |
| Atherosclerosis (PheCode 440) | T | β: 0.079 | 5E-16 | PubMed |
| Biological Mother: Cancer, Lung | T | β: 0.097 | 3E-15 | PubMed |
| Post bronchodilator FEV1 | T | β: 0.064 | 1E-13 | PubMed |
| Familial lung cancer | C | OR: 1.33 | 4E-13 | PubMed |
| Other diseases of lung (PheCode 510) | T | β: 0.07 | 3E-12 | PubMed |
| Post bronchodilator FEV1/FVC ratio | T | β: 0.012 | 9E-12 | PubMed |
| Pre bronchodilator FEV1/FVC ratio | — | β: 0.017 | 2E-11 | PubMed |
| Airflow obstruction in ever smokers | — | — | 3E-11 | PubMed |
| Lung function (FEV1/FVC) | — | — | 3E-11 | PubMed |
| Pre bronchodilator FEV1 | — | β: 0.085 | 4E-11 | PubMed |
| Smoking behaviour (cigarettes smoked per day) | C | β: 0.016 | 2E-10 | PubMed |
| Chronic obstructive pulmonary disease x current smoker interaction (main effect) | C | OR: 1.07 | 2E-8 | PubMed |
| Chronic obstructive pulmonary disease in non-current smokers | C | OR: 1.07 | 3E-8 | PubMed |