RS78534766 Unknown gene
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What This Variant Does
"Asp439Glu in ADCY7 doubles risk of ulcerative colitis http://biorxiv.org/content/biorxiv/early/2016/..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Hypothyroidism | A | OR: 0.3 | 2E-42 | PubMed |
| Hypothyroidism | A | OR: 0.29 | 9E-42 | PubMed |
| Hypothyroidism | A | OR: 0.31 | 3E-26 | PubMed |
| Eosinophil percentage of white cells | A | OR: 0.12 | 9E-17 | PubMed |
| Hypothyroidism | — | — | 1E-16 | PubMed |
| Hypothyroidism | A | OR: 0.38 | 8E-15 | PubMed |
| Ulcerative colitis | — | OR: 2.16 | 1E-14 | PubMed |
| Autoimmune thyroid disease | A | OR: 1.46 | 1E-14 | PubMed |
| Eosinophill percentage (UKB data field 30210) | A | β: 0.094 | 2E-14 | PubMed |
| Eosinophil count | A | β: 0.098 | 4E-14 | PubMed |
| Ulcerative colitis | — | — | 3E-13 | PubMed |
| Autoimmune traits | — | — | 5E-13 | PubMed |
| Inflammatory bowel disease | — | — | 2E-12 | PubMed |
| Eosinophil count | A | β: 0.097 | 1E-11 | PubMed |
| Eosinophil count | A | — | 1E-11 | PubMed |
| Treatment or medication use - levothyroxine sodium (UKB data field 20003_1141191044) | A | OR: 0.45 | 5E-10 | PubMed |
| Hypothyroidism | A | OR: 0.38 | 1E-9 | PubMed |
| Lymphocytic thyroiditis | A | OR: 0.5 | 1E-8 | PubMed |
| Lymphocytic thyroiditis | A | OR: 0.49 | 2E-8 | PubMed |
| Graves' disease | A | OR: 0.43 | 3E-8 | PubMed |