Genetic variant
rs7766070
rs7766070 is a single-letter difference in human DNA, on chromosome 6. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs7766070 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs7766070, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs7766070
- Position
- chr6:20686342
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Type 2 diabetes | A | — | 3E-416 | PubMed |
| Fasting blood glucose | A | β 0.045 | 1E-167 | PubMed |
| Hemoglobin A1c (HbA1c, mean, inv-norm transformed) | C | β 0.084 | 9E-152 | PubMed |
| Hemoglobin A1c (HbA1c, maximum, inv-norm transformed) | C | β 0.079 | 1E-137 | PubMed |
| Hemoglobin A1c (HbA1c, minimum, inv-norm transformed) | C | β 0.079 | 3E-135 | PubMed |
| Type 2 diabetes (PheCode 250.2) | C | OR 0.1 | 6E-127 | PubMed |
| Diabetes mellitus (PheCode 250) | C | OR 0.1 | 3E-124 | PubMed |
| Alanine levels | A | β 0.04 | 1E-79 | PubMed |
| Medication use (drugs used in diabetes) | A | OR 0.15 | 5E-75 | PubMed |
| Diabetes mellitus (PheCode 250) | C | β 0.092 | 2E-60 | PubMed |
| Type 2 diabetes with neurological manifestations (PheCode 250.24) | C | β 0.086 | 2E-42 | PubMed |
| Glucose levels | A | β 0.027 | 8E-35 | PubMed |
| Weight | A | β 0.032 | 6E-31 | PubMed |
| Glucose (fasting status unknown, minimum, inv-norm transformed) | C | β 0.031 | 1E-30 | PubMed |
| Metabolic syndrome | — | β 0.011 | 5E-28 | PubMed |
| Oral glucose tolerance test-2h | — | — | 4E-25 | PubMed |
| Glucose levels (UKB data field 30740) | A | β 0.024 | 9E-24 | PubMed |
| Medication use (drugs used in diabetes) | A | OR 0.12 | 3E-19 | PubMed |
| Random glucose levels | A | β 0.003 | 5E-18 | PubMed |
| Random glucose levels | A | β 0.003 | 2E-17 | PubMed |
Sources
- dbSNP: rs7766070 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies