Genetic variant
rs7694379
rs7694379 is a single-letter difference in human DNA, on chromosome 4. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs7694379 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs7694379, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs7694379
- Position
- chr4:87265357
Genome-wide association studies (14)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Sex hormone-binding globulin levels adjusted for BMI | G | β 0.02 | 6E-71 | PubMed |
| Sex hormone-binding globulin levels | G | β 0.021 | 4E-66 | PubMed |
| Alanine transaminase levels in high alcohol intake | — | β 0.012 | 2E-16 | PubMed |
| Protein quantitative trait loci (liver) | A | OR 0.29 | 5E-16 | PubMed |
| Aspartate aminotransferase platelet ratio index in high alcohol intake | — | β 0.011 | 9E-16 | PubMed |
| Aspartate transaminase levels in high alcohol intake | — | β 0.008 | 1E-13 | PubMed |
| Polyunsaturated fatty acids to monounsaturated fatty acids ratio | A | — | 2E-12 | PubMed |
| Polyunsaturated fatty acids to total fatty acids percentage | A | — | 3E-12 | PubMed |
| Linoleic acid to total fatty acids percentage | A | — | 3E-9 | PubMed |
| Platelet count | A | OR 2.13 | 9E-9 | PubMed |
| Triglycerides x depression interaction (2df test) | A | β 0.008 | 2E-8 | PubMed |
| Degree of unsaturation | A | — | 3E-8 | PubMed |
| Forns index in high alcohol intake | — | β 0.002 | 4E-6 | PubMed |
| Fibrosis-4 index in high alcohol intake | — | β 0.005 | 4E-6 | PubMed |
Sources
- dbSNP: rs7694379 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies