RS7679 Unknown gene
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What This Variant Does
"per the 23andMe blog, the minor allele of this SNP (C) was associated with decreased HDL cholesterol..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| KITLG/PLTP protein level ratio | — | OR: 0.66 | 5E-1324 | PubMed |
| CD99/KITLG protein level ratio | — | OR: 0.33 | 2E-336 | PubMed |
| Triglycerides to Total Lipids in Chylomicrons and Extremely Large VLDL percentage | C | OR: 0.13 | 4E-275 | PubMed |
| Cholesterol to Total Lipids in Chylomicrons and Extremely Large VLDL percentage | C | β: 0.097 | 1E-155 | PubMed |
| Triglyceride levels in small HDL | T | OR: 0.12 | 3E-123 | PubMed |
| Triglycerides to total lipids ratio in very small VLDL | T | OR: 0.11 | 2E-102 | PubMed |
| Triglycerides in small HDL (UKB data field 23578) | C | OR: 0.12 | 6E-93 | PubMed |
| Concentration of medium HDL particles | T | OR: 0.1 | 4E-90 | PubMed |
| Cholesteryl esters to total lipids ratio in very small VLDL | T | β: 0.1 | 4E-89 | PubMed |
| Cholesterol to total lipids ratio in very small VLDL | T | β: 0.098 | 4E-85 | PubMed |
| Phospholipids in medium HDL | T | β: 0.099 | 2E-82 | PubMed |
| Total cholesterol levels in medium HDL | T | β: 0.098 | 2E-79 | PubMed |
| Free cholesterol in medium HDL | T | β: 0.097 | 2E-78 | PubMed |
| Free Cholesterol to Total Lipids in Very Small VLDL percentage | C | β: 0.05 | 6E-78 | PubMed |
| Cholesterol esters in medium HDL | T | β: 0.096 | 2E-77 | PubMed |
| Free cholesterol to total lipids in large VLDL percentage (UKB data field 23592) | C | OR: 0.11 | 3E-77 | PubMed |
| Triglycerides to total lipids in very small VLDL percentage (UKB data field 23608) | C | OR: 0.11 | 9E-74 | PubMed |
| Triglycerides to Total Lipids in Large LDL percentage | C | β: 0.04 | 5E-70 | PubMed |
| Phospholipids to total lipids in small LDL percentage (UKB data field 23624) | C | OR: 0.11 | 3E-69 | PubMed |
| Triglyceride percentage of total lipids in intermediate-density lipoprotein | C | β: 0.068 | 8E-66 | PubMed |