RS76763715 GBA1
Upload your DNA to see your genotype for this variant.
What This Variant Does
"rs76763715, also known as N370S or Asn370Ser, is a SNP in the GBA gene associated with Gaucher disea...
Associated Conditions
Gaucher disease type I
Parkinson disease
late-onset
Dementia
Lewy body
susceptibility to
Gaucher disease
7 conditions
Akinesia
Rigidity
Gaucher disease perinatal lethal
Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome
Gaucher disease type II
Gaucher disease type III
Thrombocytopenia
GWAS Studies (4)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Parkinson disease | — | OR: 4.11 | 3E-90 | PubMed |
| Glucocerebrosidase activity | C | OR: 4.36 | 5E-43 | PubMed |
| Parkinson's disease or first degree relation to individual with Parkinson's disease | T | OR: 0.75 | 2E-22 | PubMed |
| REM sleep behavior disorder (probable or isolated) | C | OR: 2.84 | 2E-10 | PubMed |
Other Variants in GBA1