RS75932628 Unknown gene
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What This Variant Does
"rs75932628(T), a SNP in the TREM2 gene on chromosome 6 resulting in an R47H substitution, was found ...
GWAS Studies (10)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| TREM2 protein levels | T | OR: 1.01 | 3E-113 | PubMed |
| Alzheimer's disease | T | OR: 2.39 | 3E-37 | PubMed |
| Alzheimer's disease | T | OR: 2.43 | 5E-28 | PubMed |
| Alzheimer's disease (late onset) | T | OR: 2.46 | 5E-24 | PubMed |
| Cerebrospinal fluid soluble TREM2 levels | T | OR: 1.35 | 7E-19 | PubMed |
| Alzheimer's disease (age of onset) | — | OR: 2.76 | 8E-17 | PubMed |
| Alzheimer's disease (age of onset) | T | OR: 1.07 | 1E-13 | PubMed |
| Alzheimer's disease | T | OR: 2.9 | 2E-12 | PubMed |
| Alzheimer's disease | T | OR: 1.44 | 2E-12 | PubMed |
| Alzheimer's disease (adjusted for APOE e4 dosage) | T | OR: 1.1 | 2E-11 | PubMed |