RS7574865 STAT4
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What This Variant Does
"rs7574865, a SNP in the third intron of the STAT4 gene, has been reported in a large study of Swedes...
Associated Conditions
Systemic lupus erythematosus
susceptibility to
11
Systemic lupus erythematosus
susceptibility to
11
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Hypothyroidism | T | OR: 1.14 | 1E-43 | PubMed |
| Systemic lupus erythematosus | A | OR: 1.51 | 5E-42 | PubMed |
| Systemic lupus erythematosus | T | OR: 1.57 | 1E-41 | PubMed |
| Hypothyroidism | G | OR: 0.13 | 2E-29 | PubMed |
| Primary biliary cirrhosis | C | OR: 0.72 | 9E-25 | PubMed |
| Systemic lupus erythematosus | T | OR: 1.63 | 1E-21 | PubMed |
| Systemic lupus erythematosus | T | OR: 1.48 | 4E-14 | PubMed |
| Systemic lupus erythematosus | T | — | 9E-14 | PubMed |
| Systemic sclerosis | T | OR: 1.38 | 2E-13 | PubMed |
| Systemic lupus erythematosus | T | OR: 1.69 | 2E-12 | PubMed |
| Systemic sclerosis | T | OR: 1.43 | 4E-12 | PubMed |
| Hepatocellular carcinoma in hepatitis B infection | G | OR: 1.21 | 2E-10 | PubMed |
| Celiac disease or Rheumatoid arthritis | T | — | 4E-10 | PubMed |
| Autoimmune traits (pleiotropy) | T | — | 3E-9 | PubMed |
| Systemic lupus erythematosus | T | OR: 1.51 | 5E-9 | PubMed |
| Sjögren's syndrome | — | OR: 1.51 | 2E-8 | PubMed |
| Rheumatoid arthritis | T | OR: 1.11 | 9E-8 | PubMed |
| Systemic sclerosis | T | OR: 1.41 | 3E-7 | PubMed |
| Rheumatoid arthritis | T | OR: 1.16 | 3E-7 | PubMed |
| Systemic sclerosis | T | OR: 0.38 | 4E-7 | PubMed |
Other Variants in STAT4