RS7568458 Unknown gene
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What This Variant Does
"Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status"
GWAS Studies (14)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Coronary atherosclerosis (PheCode 411.4) | T | β: 0.051 | 6E-21 | PubMed |
| Ischemic heart disease (PheCode 411) | T | β: 0.046 | 7E-19 | PubMed |
| red cell diameter width (RDW, minimum, inv-norm transformed) | T | β: 0.023 | 1E-18 | PubMed |
| red cell diameter width (RDW, mean, inv-norm transformed) | T | β: 0.021 | 2E-15 | PubMed |
| Myocardial infarction (PheCode 411.2) | T | β: 0.052 | 1E-13 | PubMed |
| Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) | A | OR: 1.06 | 2E-13 | PubMed |
| Prostate cancer | T | OR: 1.11 | 1E-12 | PubMed |
| Prostate cancer | — | β: 0.1 | 4E-12 | PubMed |
| Weight | A | β: 0.008 | 1E-11 | PubMed |
| Coronary artery disease | A | OR: 1.06 | 4E-10 | PubMed |
| Prostate cancer | A | OR: 0.1 | 1E-9 | PubMed |
| Cancer (pleiotropy) | T | OR: 1.1 | 6E-9 | PubMed |
| Prostate cancer | — | OR: 0.9 | 4E-7 | PubMed |
| Prostate cancer (late onset) | — | OR: 0.9 | 2E-6 | PubMed |