RS74315329 MYOC

Health Risk Chr 1:171636338
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What This Variant Does
"rs74315329, also known as Q168X and Gln368Ter, is a nonsense mutation in the MYOC gene on chromosome...
Associated Conditions
GWAS Studies (18)
Trait Risk Allele OR / Beta P-value Study
MYOC protein levels A OR: 1.76 9E-124 PubMed
Glaucoma (primary open-angle) A OR: 1.1 1E-42 PubMed
Primary open angle glaucoma (PheCode 365.11) G OR: 1.23 2E-41 PubMed
Primary open angle glaucoma (PheCode 365.11) G OR: 1.27 1E-39 PubMed
Glaucoma (primary open-angle) OR: 1.86 7E-38 PubMed
Glaucoma (primary open-angle) A OR: 1.84 2E-34 PubMed
Glaucoma (primary open-angle) A OR: 8.24 5E-33 PubMed
Glaucoma G OR: 1.14 3E-31 PubMed
Open-angle glaucoma (PheCode 365.1) G OR: 0.75 3E-29 PubMed
Glaucoma G OR: 1.15 2E-28 PubMed
Glaucoma A OR: 2.12 2E-28 PubMed
Takes medication for Glaucoma? G OR: 1.21 4E-28 PubMed
Glaucoma A OR: 1.71 3E-27 PubMed
Intraocular pressure A OR: 2.12 1E-26 PubMed
Takes medication for Glaucoma? G OR: 1.24 1E-24 PubMed
Open-angle glaucoma (PheCode 365.1) G OR: 0.73 1E-20 PubMed
Glaucoma (PheCode 365) A 9E-16 PubMed
Glaucoma (PheCode 365) A OR: 6.53 3E-13 PubMed
Other Variants in MYOC
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