Genetic variant

rs6982502

rs6982502 is a single-letter difference in human DNA, on chromosome 8. Carrying it does not, on its own, mean you have or will develop any condition.

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What is this?

Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs6982502 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.

We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.

Why might it matter?

ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.

Do I have this variant?

If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs6982502, if your test read this position.

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Connect this with your blood results

A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.

Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.

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What should I do next?

  1. Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
  2. Put it in context. Add your blood results, so the variant can be read against what your body is doing.
  3. Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
  4. Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
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This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.

Technical details

dbSNP ID
rs6982502
Position
chr8:125467120

Genome-wide association studies (20)

TraitRisk alleleOR / betaP-valueStudy
total cholesterol (maximum, inv-norm transformed) C β 0.069 8E-147 PubMed
Glycoprotein acetyls levels T β 0.071 6E-121 PubMed
total cholesterol (mean, inv-norm transformed) C β 0.061 3E-113 PubMed
low density lipoprotein cholesterol (LDLC, maximum, inv-norm transformed) C β 0.042 2E-57 PubMed
Glycoprotein acetyls levels T β 0.043 2E-55 PubMed
total cholesterol (minimum, inv-norm transformed) C β 0.04 2E-52 PubMed
Other chronic nonalcoholic liver disease (PheCode 571.5) C OR 0.12 9E-45 PubMed
Saturated fatty acids to total fatty acids percentage C — 2E-44 PubMed
Abnormal results of function study of liver (PheCode 573.7) C OR 0.11 1E-43 PubMed
total cholesterol (maximum, inv-norm transformed) C β 0.082 1E-37 PubMed
low density lipoprotein cholesterol (LDLC, mean, inv-norm transformed) C β 0.033 6E-35 PubMed
total cholesterol (mean, inv-norm transformed) C β 0.076 8E-34 PubMed
MEGF9/MET protein level ratio — β 0.08 7E-32 PubMed
Triglyceride levels T β 0.086 1E-30 PubMed
Total cholesterol levels T β 0.083 3E-30 PubMed
Weight (minimum, inv-normal transformed) C β 0.031 6E-30 PubMed
LDL cholesterol levels x short total sleep time interaction (2df test) — OR 1.79 4E-29 PubMed
Total cholesterol levels T β 0.073 2E-27 PubMed
mean corpuscular hemoglobin (MCH, maximum, inv-norm transformed) C β 0.034 2E-24 PubMed
Multi-trait sum score — — 6E-24 PubMed

Sources