RS6894249 Unknown gene
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What This Variant Does
"Disease-associated SNPs From non-coding regions in juvenile idiopathic arthritis are located within or adjacent to functional genomic elements of human neutrophils and CD4 T Cells"
GWAS Studies (15)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Asthma or chronic rhinosinusitis | — | OR: 0.93 | 2E-39 | PubMed |
| Tryptophan betaine levels | G | OR: 0.18 | 7E-33 | PubMed |
| Serum metabolite levels | A | OR: 0.23 | 9E-26 | PubMed |
| Total cholesterol levels | — | — | 3E-22 | PubMed |
| ACY3 protein levels | G | β: 0.049 | 1E-18 | PubMed |
| Total cholesterol levels | G | β: 0.014 | 2E-16 | PubMed |
| Aspartate aminotransferase levels | A | OR: 7.14 | 1E-12 | PubMed |
| SULT2A1 protein levels | G | β: 0.039 | 7E-12 | PubMed |
| Asthma | G | β: 0.09 | 2E-11 | PubMed |
| Psoriasis | A | β: 0.066 | 3E-10 | PubMed |
| Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) | — | OR: 1.32 | 1E-9 | PubMed |
| LDL cholesterol | A | β: 0.015 | 6E-9 | PubMed |
| Vasculitis (pleiotropy) | — | — | 8E-9 | PubMed |
| Body fat percentage (adjusted for testosterone and SHBG) | — | OR: 0.12 | 1E-8 | PubMed |
| Eczema | — | — | 3E-8 | PubMed |