RS6733839 Unknown gene
Upload your DNA to see your genotype for this variant.
What This Variant Does
"rs6733839 is a SNP in the bridging integrator 1 BIN1 gene. BIN1 is a well established risk gene for ..."
GWAS Studies (20)
| Trait | Risk Allele | OR / Beta | P-value | Study |
|---|---|---|---|---|
| Alzheimer's disease | T | OR: 1.17 | 6E-118 | PubMed |
| Alzheimer's disease | T | — | 6E-92 | PubMed |
| Alzheimer's disease | T | OR: 1.18 | 4E-90 | PubMed |
| Alzheimer's disease or family history of Alzheimer's disease | — | OR: 1.15 | 2E-64 | PubMed |
| Alzheimer's disease or family history of Alzheimer's disease | — | OR: 0.16 | 1E-54 | PubMed |
| Alzheimer's disease (late onset) | T | OR: 1.22 | 7E-44 | PubMed |
| Alzheimer's disease (age of onset) | T | β: 0.065 | 2E-37 | PubMed |
| Lewy body dementia (MTAG) | T | OR: 11.68 | 2E-31 | PubMed |
| Alzheimer's disease | — | OR: 1.2 | 3E-30 | PubMed |
| Alzheimer's disease (late onset) | T | OR: 11.3 | 1E-29 | PubMed |
| Alzheimer's disease or family history of Alzheimer's disease | T | OR: 11.3 | 1E-29 | PubMed |
| Family history of Alzheimer's disease | — | OR: 1.11 | 1E-27 | PubMed |
| Alzheimer's disease | T | OR: 1.12 | 7E-26 | PubMed |
| Alzheimer's disease or HDL levels (pleiotropy) | — | — | 3E-25 | PubMed |
| Maternal history of Alzheimer's disease | — | OR: 1.12 | 4E-21 | PubMed |
| Alzheimer's disease (adjusted for APOE e4 dosage) | T | OR: 1.15 | 2E-20 | PubMed |
| Alzheimer's disease | — | OR: 1.23 | 5E-20 | PubMed |
| Serum levels of protein BIN1 | T | OR: 0.15 | 3E-14 | PubMed |
| Transmembrane protein 132C:Cytoplasmic domain levels | T | OR: 0.18 | 7E-14 | PubMed |
| Alzheimer's disease or family history of Alzheimer's disease | T | — | 6E-12 | PubMed |