Genetic variant
rs6511720
rs6511720 is a single-letter difference in human DNA, on chromosome 19. Carrying it does not, on its own, mean you have or will develop any condition.
What is this?
Your DNA is a long sequence of four letters. At a few million positions, people commonly differ by a single letter; each of those positions is called a SNP (“snip”), and rs6511720 is the catalogue number of one of them. Which letters you carry there — one copy from each parent — is your genotype.
We hold only the basic reference record for this variant: its ID and position. Many catalogued variants have never been linked to anything.
Why might it matter?
ClinVar holds no clinical classification for this variant. That is the usual case: most catalogued variants have no known effect on health.
Do I have this variant?
If you have taken a consumer DNA test (23andMe, AncestryDNA and similar), you can download its raw data file and check. Create a free account, upload the file, and this page will show the letters you carry at rs6511720, if your test read this position.
Connect this with your blood results
A gene is a fixed instruction; a blood test shows what your body is doing now. CheckMyBloods reads the two side by side, so a variant can be set against the markers it could plausibly affect.
Blood markers do not diagnose a genetic condition, and a variant does not explain a blood result on its own. Together, with symptoms and family history, they give a clinician context.
What should I do next?
- Find out whether you carry it. Reading about a variant says nothing about you until you know your genotype.
- Put it in context. Add your blood results, so the variant can be read against what your body is doing.
- Ask questions. Dr. Hemsworth, our AI assistant, can explain this variant and your results in plain English.
- Take anything that worries you to a professional. A GP or genetic counsellor can order a confirmatory test and interpret it with your history.
This page is general information drawn from public research databases. It cannot diagnose anything, and it is not a substitute for advice from a doctor or genetic counsellor who knows your history.
Technical details
- dbSNP ID
- rs6511720
- Position
- chr19:11091630
Genome-wide association studies (20)
| Trait | Risk allele | OR / beta | P-value | Study |
|---|---|---|---|---|
| Low density lipoprotein cholesterol levels | T | OR 0.24 | 1E-947 | PubMed |
| Apolipoprotein B levels | T | OR 0.23 | 9E-830 | PubMed |
| Total cholesterol levels | T | OR 0.22 | 2E-795 | PubMed |
| LDL cholesterol | T | OR 0.22 | 4E-262 | PubMed |
| Low density lipoprotein cholesterol levels | G | OR 0.23 | 1E-230 | PubMed |
| Total cholesterol in large LDL | T | OR 0.2 | 1E-213 | PubMed |
| Cholesterol esters in large LDL | T | OR 0.2 | 1E-212 | PubMed |
| Free cholesterol in large LDL | T | OR 0.2 | 2E-211 | PubMed |
| Total cholesterol levels in LDL | T | OR 0.2 | 9E-211 | PubMed |
| Total Cholesterol in IDL | T | OR 0.2 | 1E-208 | PubMed |
| Free cholesterol in IDL | T | OR 0.2 | 5E-206 | PubMed |
| Cholesterol esters in IDL | T | OR 0.2 | 8E-206 | PubMed |
| Cholesterol esters in medium LDL | T | OR 0.2 | 1E-205 | PubMed |
| Total cholesterol in medium LDL | T | OR 0.2 | 2E-204 | PubMed |
| Cholesterol esters in small LDL | T | OR 0.2 | 2E-204 | PubMed |
| Cholesterol, total | T | OR 0.19 | 5E-202 | PubMed |
| Total Cholesterol in small LDL | T | OR 0.2 | 1E-200 | PubMed |
| Phospholipids in large LDL | T | OR 0.2 | 2E-200 | PubMed |
| Phospholipids to total lipids ratio in small LDL | T | OR 0.19 | 6E-198 | PubMed |
| Total lipids in small LDL | T | OR 0.19 | 2E-188 | PubMed |
Sources
- dbSNP: rs6511720 — the reference record
- ClinVar — clinical interpretations submitted by laboratories
- SNPedia — community-written summaries
- GWAS Catalog — association studies